INFLUENCE OF THE TAIGA TICK IXODES PERSULCATUS SCHULZE, 1930 (ACARI: IXODIDAE) ON HUMORAL IMMUNE RESPONSIVENESS OF RED VOLES CLETHRIONOMYS RUTILUS PALLAS, 1779 AND FIELD MICE APODEMUS AGRARIUS PALLAS 1771 (RODENTIA: CRICETIDAE AND MURIDAE) IN NA

About authors:

А.К. Dobrotvorsky, Institute for Systematics and Ecology of Animals, Siberian Division of the Russian Academy of Sciences, 11 Frunze Str., Novosibirsk, 630091  Russia

M.P. Moshkin, Institute of Systematics and Ecology of Animals, Siberian Division of the Russian Academy of Sciences Novosibirsk, 630091 Russia
V.V. Panov, Institute of Systematics and Ecology of Animals, Siberian Division of the Russian Academy of Sciences Novosibirsk, 630091 Russia
V.V. Мак , Institute of Systematics and Ecology of Animals, Siberian Division of the Russian Academy of Sciences Novosibirsk, 630091 Russia

Acknowledgments:

This study was supported in part by a grant from the Russian Foundation for Basic Research (96-04-50113). We thank Professor Andrei N.Alekseev (Zoological Institute, the Russian Academy of Sciences, St. Peters-burg, Russia) for valuable notes to the manuscript. We are also grateful to Dr. Steven T. Knick (US Geological Survey, Boise, ID, USA) for useful com-ments and the English editing of the paper.

Annotation:

Based on the five-year population study of red voles Clethrionomys rutilus Pallas and field mice Apodemus agrarius Pallas in southern West Siberia, we analysed the distribution of immature stages of ticks Ixodes persulcatus on different demographic groups of the hosts, and seasonal changes of their incidence in the populations. We assessed primary humoral immune response of the voles and mice (splenic plaque -forming cells) to antigenic challenge (injection of sheep erythrocytes) in respect to occurrence of these parasites. Immune responses in immature and mature voles, which where parasitized by I. persulcatus at capture, were significantly higher as compared to non-infested hosts. For field mice similar effect of tick infestation was observed only in immature summerborn rodents. We discuss possible mechanisms of influence of ticks on vari-ability of immune reactions in the populations.

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